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It became known as Librium, a mild drug far less likely to cause sleepiness or addiction than anything then Fedex generic valium on the market as a tranquilizer. The benzodiazepines rose in popularity as an improvement upon barbiturates, which have a comparatively narrow therapeutic index, and are far more sedating at therapeutic doses. They can save lives where people are suffering repeated or continuous convulsions caused by drugs or poisons. But no convincing endodiazepine has yet appeared and Squires, one of the discoverers of the benzodiazepine receptor, believes that there is no endogenous ligand and no reason to assume that one exists.